CINCHSCOPE examples of improvED Resolution over widefield or confocal microscopy


Comparison of single plane confocal and FINCH confocal images (CINCH) of the same plane of mouse retinal astrocytes labeled with Cy3. Slide courtesy of Dr. Gerard Lutty and Dr. Adam Wenick, Johns Hopkins University Wilmer Eye Institute. Images generated using CellOptic’s CINCHSCOPE with 100X 1.4 NA objective.

Mouse brain astrocytes. Blue: DAPI, Green S100B, Red GFAP. Maximum intensity projection of 13 planes, 0.25 micron/slice.  Both Confocal and CINCH images have been deconvolved. Slide courtesy of Lynne Holtzclaw, NICHD Microscopy & Imaging Core Facility at NIH. Images generated using CellOptic’s CINCHSCOPE with 100X 1.4 NA objective.

Mouse brain astrocytes. Blue: DAPI, Green S100B, Red GFAP. Slide courtesy of Lynne Holtzclaw, NICHD Microscopy & Imaging Core Facility at NIH.  Comparison of single plane confocal and CINCH (confocal FINCH) images using CellOptic’s CINCHSCOPE with 20X 0.75 NA objective.

Fundic stomach H&E Fluorescence Cy3 and Cy5 channels. Images generated using CellOptic’s CINCHSCOPE with 100X 1.4 NA objective.

HeLa cell stained with Golgi and lysosomal protein markers. Blue: TGN46, Green: Giantin, Red: Lamp2. Slide courtesy of Dr. Vladimir Lupashin and Tetyana Kudlyk, University of Arkansas for Medical Science. Images generated using CellOptic’s CINCHSCOPE with 100X 1.4 NA objective.

Fluorescent mixed pollen grains imaged in the Cy3 channel. Images generated using CellOptic’s CINCHSCOPE with 100X 1.4 NA objective.